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Part of our Synogut overview. Last checked October 19, 2026.
Synogut ingredients are 10 fibers, plant materials, a clay and a probiotic, all listed inside one 1.5 g proprietary blend per 2-capsule serving[1]. The label gives no amount for any single ingredient, so the average works out to about 150 mg each. Other ingredients are gelatin, magnesium stearate and silicon dioxide, which means the capsules are not vegetarian. The label also says "Contains Tree Nuts (Black Walnut)".
Synogut ingredients at a glance
The table lists every item on the Synogut label, in label order, with what the sales copy claims and how strong the human evidence is at the dose a capsule could hold.
| Ingredient | Role claimed | Amount disclosed? | Evidence grade |
|---|---|---|---|
| Psyllium husk | Fiber, regularity | No | Moderate at grams; weak here |
| Bentonite clay | "Cleans" the intestines | No | Avoid without a lead test |
| Black walnut hull | Parasite story | No | Weak, no human data |
| Oat bran | Fiber | No | Moderate for LDL at 3 g beta-glucan; weak here |
| Flaxseed | Fiber | No | Limited |
| Prune | Regularity | No | Moderate at food doses; weak here |
| Aloe vera leaf | Gut lining | No | Weak, IBS trials null |
| L. acidophilus | Probiotic | No strain, no CFU | Weak |
| Apple pectin | Fiber | No | Limited |
| Glucomannan | Fiber | No | Moderate for LDL at 3 g; weak here |
What is in each ingredient, and what does research say?
Most Synogut ingredients have human research, but nearly all of it used doses far above a 150 mg average share. Here is each one in turn.
Psyllium husk
Psyllium is a bulk-forming fiber from Plantago ovata seed husks, used in the US as a laxative[2]. A meta-analysis of 28 trials with 1,924 people found LDL cholesterol fell by 0.33 mmol/L at a median of about 10.2 g a day[3]. In type 2 diabetes it lowered fasting glucose; in people with normal blood sugar it did not. Grade: moderate at gram doses, weak in this blend.
Bentonite clay
Bentonite is an absorbent clay. The only trial data are for medical-grade smectite in children with acute diarrhea, where a Cochrane analysis of 18 trials found it may shorten illness by about 1 day, with low certainty[4]. No human trial of food-grade bentonite for adult gut health was found. In 2016 the FDA warned consumers not to swallow one bentonite product after finding high lead levels[5]. Synogut publishes no heavy-metal test.
Black walnut hull
Black walnut hull comes from Juglans nigra. PubMed has no human trial of it for digestion, parasites or any gut outcome. It is a tree nut allergen, with allergens from both walnut species characterized[6]. Grade: weak, and avoid with a tree nut allergy.
Oat bran
Oat bran supplies beta-glucan, a soluble fiber. A meta-analysis of 28 trials found 3 g a day or more of oat beta-glucan lowered LDL by 0.25 mmol/L, with no change in HDL or triglycerides[7]. About 150 mg of oat bran holds far less than 3 g of beta-glucan.
Flaxseed
In one functional constipation trial, flaxseed flour raised weekly bowel movements from 2 to 7, vs 2 to 6 with lactulose[8]. NCCIH says raw or unripe flaxseed has potentially toxic compounds and high doses can cause bloating and diarrhea[9]. Grade: limited.
Prune
Prunes at 50 g twice a day, about 12 prunes, beat psyllium on weekly complete bowel movements in a 40-person crossover trial[10]. A capsule share is roughly 150 mg. Grade: moderate at food doses, weak here.
Aloe vera leaf
In a trial with 160 completers, aloe extract was no better than control for IBS: 39% responders vs 45%[11]. The label does not say whether it uses gel, latex or whole leaf. Grade: weak.
Lactobacillus acidophilus
One named strain, DDS-1, lowered IBS abdominal pain scores at 10 billion CFU a day[12]. Synogut lists no strain and no CFU count, and NCCIH says effects of one strain do not carry to another[13]. Grade: weak.
Apple pectin
Pectin added to tube feeds cut diarrhea risk in a 12-trial analysis of 1,405 ICU patients[14]. One trial of 87 people with diarrhea-type IBS also reported better stool form. Grade: limited.
Glucomannan
Konjac glucomannan lowered LDL at about 3 g a day[15], but its weight-loss effect was not significant across 8 trials[16]. It absorbs up to 50 times its weight in water. Grade: moderate for LDL at 3 g, weak here.
How transparent is the Synogut formula?
The Synogut formula names every ingredient but hides every amount. A proprietary blend lets a brand list 10 items under one total, so 1.5 g divided by 10 gives about 150 mg each, and the real split could be very uneven.
That matters because the cheapest items could fill most of the blend. The label also leaves out:
- the strain and CFU count of L. acidophilus
- whether ingredients are whole powders or extracts
- the aloe form and its aloin content
- the bentonite source and any heavy-metal test
Some copycat pages list only part of the ingredient set. Trust the bottle label shown on the vendor references page, checked October 19, 2026, over third-party lists.
Ingredient safety and interactions
Three ingredients carry the main safety notes: bentonite clay (lead risk in unverified clay), black walnut hull (tree nut allergy) and aloe leaf (NCCIH links oral aloe leaf extracts to cases of acute hepatitis)[17]. MedlinePlus says not to take digoxin, aspirin or nitrofurantoin within 3 hours of psyllium[2]. Flaxseed has a theoretical interaction with blood thinners[9].
The label itself says Synogut is not for people on prescription medication without a doctor's advice. The details, plus who should skip it, are on our Synogut side effects page.
Do these ingredients prove Synogut works?
No. Ingredient research shows what an ingredient did at a studied dose, form and population, and Synogut matches none of the strongest studies on dose. No trial of the finished capsule has been published.
We set out what the evidence does and does not support on our does Synogut work page, and the serving directions are on how to take Synogut.
Back to the Synogut overview.
Frequently asked questions
What are the ingredients in Synogut?
The label lists psyllium husk, bentonite clay, black walnut hull, oat bran, flaxseed, prune, aloe vera leaf, L. acidophilus, apple pectin and glucomannan in a 1.5 g blend. Other ingredients are gelatin, magnesium stearate and silicon dioxide.
How much of each ingredient is in Synogut?
The label does not say. All 10 ingredients sit in one 1.5 g proprietary blend per 2-capsule serving, which averages about 150 mg each. The real split could be uneven, and no single amount is printed.
Is Synogut vegetarian?
No. The label lists gelatin among the other ingredients, which is an animal product, so the capsules are not vegetarian or vegan. The label also warns that the product contains tree nuts from black walnut.
Does Synogut contain allergens?
Yes. The label says it contains tree nuts (black walnut). It adds that the facility may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish. Anyone with a tree nut allergy should avoid it.
How many CFU of probiotic does Synogut have?
The label does not give a CFU count or a strain name for L. acidophilus. Probiotic trials test named strains at stated doses, such as DDS-1 at 10 billion CFU a day, so this ingredient cannot be matched to a study.
Sources
- Synogut Supplement Facts label image. Synogut vendor site (thesynogut.com), read October 19, 2026.
- Psyllium. MedlinePlus Drug Information, U.S. National Library of Medicine, read October 19, 2026.
- Psyllium fiber and LDL cholesterol, meta-analysis of 28 randomized trials. PubMed, U.S. National Library of Medicine, read October 19, 2026.
- Smectite for acute infectious diarrhea in children, Cochrane analysis of 18 trials. PubMed, U.S. National Library of Medicine, read October 19, 2026.
- FDA Warns Consumers Not to Use Best Bentonite Clay (archived copy). U.S. Food and Drug Administration, March 23, 2016, read October 19, 2026.
- Walnut allergens from Juglans regia and Juglans nigra. PubMed, U.S. National Library of Medicine, read October 19, 2026.
- Oat beta-glucan and blood cholesterol, meta-analysis of 28 randomized trials. PubMed, U.S. National Library of Medicine, read October 19, 2026.
- Flaxseed flour vs lactulose in functional constipation, randomized trial. PubMed, U.S. National Library of Medicine, read October 19, 2026.
- Flaxseed and Flaxseed Oil: Usefulness and Safety. National Center for Complementary and Integrative Health (NCCIH), read October 19, 2026.
- Prunes vs psyllium for chronic constipation, randomized crossover trial. PubMed, U.S. National Library of Medicine, read October 19, 2026.
- Aloe vera extract in irritable bowel syndrome, randomized controlled trial. PubMed, U.S. National Library of Medicine, read October 19, 2026.
- Lactobacillus acidophilus DDS-1 in irritable bowel syndrome, randomized placebo-controlled trial. PubMed, U.S. National Library of Medicine, read October 19, 2026.
- Probiotics: What You Need To Know. National Center for Complementary and Integrative Health (NCCIH), read October 19, 2026.
- Pectin-supplemented tube feeding and diarrhea in ICU patients, meta-analysis of 12 trials. PubMed, U.S. National Library of Medicine, read October 19, 2026.
- Konjac glucomannan and LDL cholesterol, meta-analysis. PubMed, U.S. National Library of Medicine, read October 19, 2026.
- Glucomannan for weight loss in overweight adults, meta-analysis of 8 randomized trials. PubMed, U.S. National Library of Medicine, read October 19, 2026.
- Aloe Vera: Usefulness and Safety. National Center for Complementary and Integrative Health (NCCIH), read October 19, 2026.
This page is general information, not medical advice. Dietary supplements are not reviewed by the FDA for safety or effectiveness before they are sold and are not intended to diagnose, treat, cure or prevent any disease. Talk to your doctor before taking any supplement, especially if you are pregnant, nursing, take medication or have a health condition.
